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| Product Name | PQBP1, Recombinant, Human, aa1-265, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Source: Recombinant corresponding to aa1-265 from human PQBP1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~33kD (289aa), confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMPLPVA LQTRLAKRGI LKHLEPEPEE EIIAEDYDDD PVDYEATRLE GLPPSWYKVF DPSCGLPYYW NADTDLVSWL SPHDPNSVVT KSAKKLRSSN ADAEEKLDRS HDKSDRGHDK SDRSHEKLDR GHDKSDRGHD KSDRDRERGY DKVDRERERD RERDRDRGYD KADREEGKER RHHRREELAP YPKSKKAVSR KDEELDPMDP SSYSDAPRGT WSTGLPKRNE AKTGADTTAA |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PQBP1, Recombinant, Human, aa1-265, His-Tag (Polyglutamine-binding Protein 1, PQBP-1, 38kD Nuclear Protein Containing a WW Domain, Npw38, Polyglutamine Tract-binding Protein 1, NPW38, JM26) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45454 |
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| Order / More Info | PQBP1, Recombinant, Human, aa1-265, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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