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| Product Name | Polymerase Acidic Protein, Recombinant, Influenza A virus, aa124-247, His-Tag (PA) |
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| Description | Purity ~90% (SDS-PAGE). Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. Source: Recombinant protein corresponding to aa124-247 from Influenza A virus Polymerase acidic protein, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~18.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9IQ47 |
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| Catalog # | 406022 |
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| Order / More Info | Polymerase Acidic Protein, Recombinant, Influenza A virus, aa124-247, His-Tag (PA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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