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| Product Name | DHDDS, Recombinant, Human, aa1-333, GST-Tag (Dehydrodolichyl Diphosphate Synthase) |
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| Description | Purity ~90% (SDS-PAGE). With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Source: Recombinant protein corresponding to aa1-333 from human DHDDS, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~65.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cis-isoprenyltransferase |
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| Gene, Accession, CAS # | SwissProt: Q86SQ9 |
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| Catalog # | 373049 |
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| Order / More Info | DHDDS, Recombinant, Human, aa1-333, GST-Tag (Dehydrodolichyl Diphosphate Synthase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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