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| Product Name | MLK2, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 2, MAP3K10, MST) |
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| Description | Purified (~70-90%). MLK2 or mixed-lineage kinase 2 is a member of the serine/threonine kinase family, which activates MAPK8 JNK and MKK4/SEK1. MLK2 itself can be phoshorylated, and activated by JNK kinases. MLK2 is also known as mitogen-activated protein kinase kinase kinase 10 (MAP3K10). MLK2 functions preferentially on the JNK signaling pathway which is involved in nerve growth factor (NGF) induced neuronal apoptosis. MLK2 was isolated as a cDNA fragment from MKN28 gastric cancer cell library using degenerate PCR. MLK2 is highly expressed in brain, skeletal muscle, and testis. Source: Recombinant protein corresponding to human MLK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~76kD Specific Activity: 48nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002446 |
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| Catalog # | 500272 |
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| Order / More Info | MLK2, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 2, MAP3K10, MST) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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