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| Product Name | CTGFL/WISP-2, Recombinant, Human (Connective Tissue Growth Factor-Like protein, CCN5, CT-58) |
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| Description | Purity ~95% (SDS-PAGE). CTGFL/WISP-2 is a 28.6kD protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Source: Recombinant protein corresponding to 228aa residues from human CTGFL/WISP-2, expressed in E. coli. Molecular Weight: ~24.3kD Biological Activity: Determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 is between 10-20ng/ml in the presence of 15ng/ml of human IGF-II. Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGF |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Connective Tissue Growth Factor-Like protein, CCN5, CT-58 |
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| Gene, Accession, CAS # | CTGFL, Gene ID: 8839, Accession: O76076 |
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| Catalog # | 219673 |
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| Order / More Info | CTGFL/WISP-2, Recombinant, Human (Connective Tissue Growth Factor-Like protein, CCN5, CT-58) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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