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| Product Name | NXT1, Recombinant, Human, aa1-140, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. This protien heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. Source: Recombinant corresponding to aa1-140 from human NXT1, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASVDFKTYV DQACRAAEEF VNVYYTTMDK RRRLLSRLYM GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT VLVVICGSVK FEGNKQRDFN QNFILTAQAS PSNTVWKIAS DCFRFQDWAS Molecular Weight: ~18kD (160aa) confirmed by MALDI-TOF |
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| Size | 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NXT1, Recombinant, Human, aa1-140, His-Tag (NTF2-related Export Protein 1, NTF2-like Export Factor 1) |
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| Gene, Accession, CAS # | Accession: NP_037380 |
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| Catalog # | N8570-03 |
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| Order / More Info | NXT1, Recombinant, Human, aa1-140, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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